Diagnostic accuracy of the second generation dual-source dual-energy CT myocardial perfusion imaging in patients with suspicious myocardial infarction
Han Ruijuan1,Sun Kai1,2,Li Kuncheng3,Zhao Ruiping1,Li Wenhuan3,Bai Shuancheng4，Wang Junyan5,Li Hongyu1,Lu Yaojun1
1Department of Translational Medicine Center,2Department of Medical Imaging Research Institute,4Department of Anesthesiology,5Department of ICU,Central Hospital of Baotou,Baotou 014040,China;3Department of Imaging,Xuanwu Hospital,Beijing 100020,China
Abstract：ObjectivesTo evaluate the diagnostic accuracy of the second generation dual-source dual-energy CT myocardial perfusion imaging in patients with suspicious myocardial infarction.MethodsFifty-six patients underwent dual-source dual-energy myocardial perfusion imaging,of which forty patients had follow-up results ［confirmed by catheter coronary angiography，cardiac troponin I elevation and Electrocardiogram (ECG) changes and evolution of acute myocardial infarction］ within 30 days．Catheter coronary angiography and clinical data served as the standard of references.The sensitivity,specificity and positive and negative predictive values of the second generation dual-source dual-energy CT myocardial perfusion in the detection of myocardial infarction were evaluated.The coronary image quality and radiation dose were evaluated. Results Diagnostic accuracy：the sensitivity,specificity and positive and negative predictive values were 95.0%,97.0%,86.4% and 98.9%，respectively.Coronary image quality：one patient with non-diagnostic images was due to motion artifacts occurred at the right coronary artery and left circumflex artery;another patient′s vessels were unassessable due to the motion artifacts induced by high heart rate variability;the other patients′ image quality were good.Radiation dose:the average effective radiation dose was (6.1±1.5)mSv.ConclusionOne-step dual-source dual-energy CT myocardial perfusion scan combined with coronary CTA provide high diagnostic accuracy for detecting myocardial infarction with lower radiation exposure in patients with suspicious myocardial infarction.
