Abstract:ObjectiveTo study the bone mineral density (BMD) changes of elderly patients with type 2 diabetes by dual energy x-ray absorptiometry (DXA) machine.MethodsTaking the methodological standards of BMD measurement of International Society for Clinical Densitometry (ISCD) as criteria,one hundred and eighteen elderly patients with type 2 diabetes and ninety-seven elderly healthy volunteers were recruited in the study and underwent BMD measurement,respectively.Lumbar spine,proximal femur and 1/3 of non-dominant side forearm bone were selected.Then quantitative analysis was made to compare differences of the BMD in the two groups of subjects. ResultsThe BMD absolute value of lumbar spine,proximal femur and 1/3 of non-dominant side forearm bone in type 2 diabetes were (0.79±0.21)g/cm2,(0.78±0.19)g/cm2 and (0.65±0.18)g/cm2,respectively,which were significantly lower than those of the healthy control group (0.99±0.17)g/cm2,(0.91±0.14)g/cm2 and (0.89±0.16)g/cm2,(t=-6.53,-4.12,-5.37;all P<0.01).The BMD of lumbar spine,proximal femur and 1/3 of non-dominant side forearm bone in elderly male patients with type 2 diabetes were [(0.78±0.20)g/cm2,(0.74±0.23)g/cm2,(0.66±0.18)g/cm2],which were significantly higher than those in female patients [(0.74±0.23)g/cm2,(0.69±0.15)g/cm2,(0.65±0.15)g/cm2],(t=-5.62,-5.49,-4.37;all P<0.01).The BMD of lumbar spine,proximal femur and 1/3 of non-dominant side forearm bone in healthy men were [(1.06±0.14)g/cm2,(0.94±0.11)g/cm2,(0.95±0.14)g/cm2],which were significantly higher than those in female [(0.98±0.13)g/cm2,(0.93±0.14)g/cm2,(0.91±0.13)g/cm2],(t=-6.19,-7.38,-3.49;all P<0.01).ConclusionThe BMD of lumbar spine, proximal femur and forearm bone of elderly patients in all ages with type 2 diabetes are lower than those of elderly healthy people.
朱林波 王淑侠 聂秋容. 老年2型糖尿病患者骨矿密度研究[J]. 中华诊断学电子杂志, 2015, 3(3): 185-187.
Zhu Linbo,Wang Shuxia,Nie qiurong. The research on the bone mineral density of elderly patients with type 2 diabetes. zhzdx, 2015, 3(3): 185-187.