Abstract：ObjectiveTo determine whether EEG spectral analysis could be used for the analysis of animal models with blast traumatic brain injury.MethodsWe built animal traumatic model using TNT bomb without fragments.All the 15 goats were divided into 3 groups according their brain pathology change.We recorded EEG from the animals at the time before bomb exploring as well as 3 hours after blast.Then,we assessed EEG spectral differences from 1 to 30 Hz and compared EEG spectral with different groups,following with alculating the absolute power value in each band and (δ+θ)/(α+β) value.ResultsThe injury group′s spectral power values with 3Hz、4Hz、5Hz and 6Hz were （6.55±2.82）μV、（4.71±0.93）μV、（3.47±0.76）μV and （2.82±0.54）μV.The healthy control group′s spectral power values with 3Hz、4Hz、5Hz and 6Hz were （3.20±0.58）μV、（3.16±0.40）μV、（2.66±0.34）μV and （2.15±0.10）μV.It′s of significant difference between the two groups,the P value was 0.031,0.009,0.049 and 0.026. The healthy control group′s spectral value of δ band was （3.20±0.99）μV and θ band was （2.27±0.64）μV and (δ+θ)/(α+β) was （1.35±0.46）μV.The injury group′s spectral value of δ band was （9.81±1.06）μV and θ band was （4.97±1.41）μV and (δ+θ)/(α+β) was （3.19±0.74）μV， which were significantly higher than the healthy control group(P=0.045，0.048，0.024). The no injury group′s spectral value of δ band was （3.01±0.93）μV and θ band was （2.31±0.80）μV and (δ+θ)/(α+β) was （1.47±0.32）μV，which were similar with the healthy control group (P=0.794，0.940，0.704).ConclusionEEG power spectral analysis can be used as a flexible tool to demonstrate the animal model with traumatic brain injury.
