Prostate imaging reporting and data system (PI-RADS) for assessment of pathologic outcomes and clinical characteristics in patients with prostate cancer confirmed by biopsy
Abstract:ObjectiveTo explore the prostate imaging reporting and data system (PI-RADS) for assessment of pathologic outcomes and clinical characteristics after radical prostatectomy (RP) who confirmed by biopsy.MethodsThe patients who underwent multiple parameter MRI (mpMRI) and were diagnosed by prostate cancer (PCa) from January 2013 to June 2017 were reviewed retrospectively.Of which,81 patients were screened after RP in patients with GS 3+4=7 tumor at biopsy.Two radiologists assessed mpMRI with double blind method and assigned PI-RADS categories (categories 1~5),which compared to the GS,and the presence of extracapsular extension (ECE) after RP.Results53.1% of patients (43/81) had ECE,and 2.5% (2/81) had their tumors downgraded to GS3+3=6,whereas 21.0% (17/81) had GS4+3=7PCa after RP.PI-RADS showed moderate accuracy for the diagnosis of GS4+3≥7 tumors (AUC,0.65;95% CI,0.54~0.77) and moderate accuracy for the ECE (AUC,0.72;95%CI,0.62~0.87).The sensitivity of PI-RADS score of 3 or higher was 100% for diagnosis of GS4+3=7PCa.PI-RADS category of 4 or higher for diagnosis of PCa were 94.1% and 23.4%,respectively.Interobserver agreement was moderate (κ=0.43).ConclusionFor GS3+4=7 cancers detected at biopsy,higher PI-RADS categories are associated with upgrading to GS4+3=7 and the presence of ECE after RP.
张立涛 李秀娟 朱晓琳 马振波 马得廷 谢元忠. 前列腺成像报告和数据系统与活检证实的前列腺癌根治术后患者临床及病理学特征比较[J]. 中华诊断学电子杂志, 2017, 5(4): 267-271.
Zhang Litao,Li Xiujuan,Zhu Xiaolin,Ma Zhenbo,Ma Deting,Xie Yuanzhong. Prostate imaging reporting and data system (PI-RADS) for assessment of pathologic outcomes and clinical characteristics in patients with prostate cancer confirmed by biopsy. zhzdx, 2017, 5(4): 267-271.