Abstract：ObjectiveTo explore the ischemic postconditioning effects on heart failure after acute myocardial infarction. MethodsThere were 200 myocardial infarction patients within 12h on emergency PCI, of which 100 patients received routine PCI therapy (control group), and the other 100 patients received ischemic postconditioning therapy(IPTC group). The parameters between the two groups of CKMB, cTnI, BNP, and the LVEF, LVEDD by echocardiography were observed. Results3 days after myocardial infarction the cTnI level of control group （40.40±3.85）ng/ml was higher than that of IPTC group （23.12±2.36）ng/ml, the difference was statistically significant (t=7.30,P＜0.05). 14 days after myocardial infarction the BNP level of control group (2595±239)pg/ml was higher than that of IPTC group (1391±154)pg/ml, the difference was statistically significant (t=6.54,P＜0.05). 3 months after myocardial infarction the LVEF data of normal control group （48.16±4.62）mm was lower than that of IPTC group （57.11±4.43）mm, the difference was statistically significant (t=21.50,P＜0.05). 6 months after myocardial infarction the LVEF data of normal control group （49.78±6.22）mm was lower than that of IPTC group （60.41±3.94）mm, the difference was statistically significant (t=4.67,P＜0.05). 6 months after myocardial infarction the LVEDD data of control group （52.19±6.42）mm was higher than that of IPTC group （44.24±5.47）mm, the difference was statistically significant (t=7.70,P＜0.05). ConclusionIschemic postconditioning could improve cardiac function after myocardial infarction, and reduce the acute myocardial infarction injury.
