Analysis of clinical features of secondary hemophagocytic syndrome with liver failure as the main manifestation
Peng Yong1,2, Liu Yuanyuan1, Lei Xu1, Li Shan1, Li Jinke1, Tan Huabing1
1Department of Infections Disease, Shiyan People′s Hospital Affiliated to Hubei University of Medicine, Shiyan 442000, China; 2Department of Infections Disease, People′s Hospital of Zhushan County, Zhushan 442200, China
Abstract：ObjectiveTo investigate the clinical features of secondary hemophagocytic syndrome (HPS)， or named haemophilic lymphohistiocytic hyperplasia (HLH). MethodsA case of secondary HPS with liver failure as the main manifestation from Department of Infections Disease of Shiyan People′s Hospital on September 27, 2017 was introduced, and literatures were reviewed. ResultsThe clinical manifestations of the patient were fever and splenomegaly, blood tests showed that hemoglobin was 88g/L, platelet was 36×109/L, neutrophil count was 0.72×109/L, triglyceridemia was 3.8mmol/L, fibrinogen was 1.15g/L, natural killer percentage was 0.02%, ferritin was 2000.0μg/L, and lactate dehydrogenase was 560U/L. According to the above test results, HPS could be diagnosed. In line with the diagnostic criteria for acute liver failure, the level of serum total bilirubin was 189.6μmol/L, the prothrombin activity was 39.1%, the level of serum alanine aminotransferase was 279U/L, the level of serum aspartic aminotransferase was 221U/L. ConclusionLiver failure can be the main manifestation of secondary HPS, and scientific diagnosis of secondary HPS is crucial.
彭勇 刘园园 雷旭 李姗 李金科 谭华炳. 以肝功能衰竭为主要表现的继发性噬血细胞综合征的临床诊断学特征分析[J]. 中华诊断学电子杂志, 2019, 7(4): 269-272.
Peng Yong, Liu Yuanyuan, Lei Xu, Li Shan, Li Jinke, Tan Huabing. Analysis of clinical features of secondary hemophagocytic syndrome with liver failure as the main manifestation. zhzdx, 2019, 7(4): 269-272.
