Abstract：ObjectiveTo investigate the diagnostic features of hemichorea associated with non-ketotic hyperglycemia (HC-NH). MethodsThe clinical data of a patient with HC-NH admitted to the Neurology Department of Qingpu Branch of Zhongshan Hospital Affiliated to Fudan University on December 8, 2019 was retrospectively analyzed, and relevant literatures were reviewed. ResultsA 51-year-old female patient was admitted to the hospital for dry mouth and polydipsia for more than 4 months, and involuntary movement of the right limb for 1 week. The clinical manifestations were hemichorea-like movements, increased blood sugar, and positive blood ketones. Brain CT showed the abnormally higher density shadow of the left lenticular nucleus. Brain MRI T1WI showed abnormally high signal in the left basal ganglia region, T2WI, fluid attenuated inversion recovery sequence (FLAIR) and diffusion weighted imaging (DWI) showed slightly low signal changes. The patient was diagnosed with HC-NH, and the blood glucose was actively controlled. After treatment with tiapride hydrochloride and diazepam, the patient′s chorea-like symptoms disappeared 1 month later. Brain CT reexamination showed normal and the condition was stable without recurrence so far. ConclusionChorea-like symptoms, high blood sugar, positive blood ketones, abnormal signal in the basal ganglia region in brain CT or MRI, are important diagnostic features of HC-NH.
余慧 杨位霞. 非酮症性高血糖偏侧舞蹈症的临床特征并文献复习[J]. 中华诊断学电子杂志, 2022, 10(1): 26-30.
Yu Hui, Yang Weixia. Clinical features of hemichorea associated with non-ketotic hyperglycemia and literature review. zhzdx, 2022, 10(1): 26-30.
