Abstract：ObjectiveTo investigate the diagnostic characteristics of pulmonary abscess caused by Prevotella. MethodsThe clinical data of 1 patient who was admitted to the Department of Respiratory and Critical Care Medicine of General Hospital of Western Theater Command on August 22, 2021 was retrospectively collected and the related literatures were reviewed. ResultsA 51-year-old male patient with fever and chest pain had no obvious pathogenic bacteria in routine sputum, pleural effusion, and blood bacterial cultures. The infection indicators, such as procalcitonin and blood routine, were significantly elevated, and the chest computed tomography (CT) scans revealed the development of lung abscess. Meropenem, moxifloxacin, and metronidazole were used as an initial antiinfective treatment empirically for about a month, but the results were ineffective. Finally, the prevotella was detected as the pathogenic bacteria from lavage fluid and blood by metagenomic next generation sequencing (mNGS). ConclusionsThe pathogen Prevotella is opportunistic. The use of mNGS in the etiological identification of complex infections is worthy of further acclaim in clinical practice when infected patients fail to respond to standard empirical treatment.
