Research progress on biological function of mitochondria-associated endoplasmic reticulum membranes and its role in related diseases
Yu Lu1， Li Yonghua2
1College of Clinical Medicine, Jining Medical University, Jining 272013, China； 2Department of Ophthalmology, the Affiliated Hospital of Jining Medical University, Jining 272029, China
Abstract："Mitochondrialassociated endoplasmic reticulum membranes (MAMs)" refer to the region where the endoplasmic reticulum and the outer membrane of the mitochondria come into contact. MAMs contain carrier proteins, channel proteins, and membrane proteins. MAMs can take part in a wide range of biological processes, such as mitophagy, Ca2+ release, inflammatory response, lipid metabolism, and neoangiogenesis. They can also affect the disease development, such as like cardiovascular disease, diabetes, and cancer. This essay′s primary objective is to summarize the numerous biological functions of MAMs and how those functions relate to various diseases.
于露1李永华2. 线粒体相关内质网膜的生物学功能及其在相关疾病中作用的研究进展[J]. 中华诊断学电子杂志, 2022, 10(4): 284-288.
Yu Lu1， Li Yonghua2. Research progress on biological function of mitochondria-associated endoplasmic reticulum membranes and its role in related diseases. zhzdx, 2022, 10(4): 284-288.
