Abstract:The dynamic and ordered process of bacterial biofilm production, which involves numerous components, can cause a variety of chronic illnesses. Major facilitator superfamily (MFS), one of the six bacterial efflux pump families, is one of the largest superfamilies of membrane transport proteins. Recent studies have revealed a close connection between the MFS membrane transporters and the formation of bacterial biofilm. The former has the greatest influence on biofilm formation due to three factors: the transport of substrates containing biofilm matrix components, the induction of biofilm matrix component synthesis, and the metabolic process of biofilm formation.In this review, the concept and transport mechanism of MFS membrane transporters, and their possible mechanisms affecting the formation of bacterial biofilm are summarized to provide a theoretical basis for related research on bacterial biofilm.
杨锐富 周燕斌. 主要协同转运蛋白超家族膜转运蛋白与细菌生物膜形成的相关性研究进展[J]. 中华诊断学电子杂志, 2023, 11(2): 77-81.
Yang Ruifu, Zhou Yanbin.
Research progress on the correlation of major facilitator superfamily membrane transporters and bacterial biofilm formation. zhzdx, 2023, 11(2): 77-81.