Research progress of autophagy regulating cell ferroptosis and the effects of ferroptosis in tumors
Li Minchang1, Ma Changlin2
1College of Clinical Medicine, Jining Medical University, Jining 272013, China; 2Department of Hepatobiliary Surgery, the First People′s Hospital of Jining, Jining 272002, China
Abstract：Ferroptosis is a new type of cell death related to iron overload and lipid peroxidation, which is different from traditional apoptosis and occurs during tumor development. Autophagy is a degradation and circulatory system that is essential for removing waste from cells. According to researches, autophagy may disrupt intracellular homeostasis and lead to ferroptosis, which has been linked to tumor development. In order to provide new ideas for tumor treatment, this article summarizes the mechanism of autophagy regulating ferroptosis and briefly introduces the role of autophagy and ferroptosis in different tumors.
李民昌 马长林. 自噬调控的细胞铁死亡及在肿瘤中影响的研究进展[J]. 中华诊断学电子杂志, 2023, 11(2): 140-144.
Li Minchang, Ma Changlin. Research progress of autophagy regulating cell ferroptosis and the effects of ferroptosis in tumors. zhzdx, 2023, 11(2): 140-144.
