Abstract：Author：Li Xinfeng,Email:surgone 0107@163.com
【Abstract】ObjectiveTo investigate clinical value of early continuous blood purification (CBP)in intra abdominal hypertension(IAH) of postoperative abdominal trauma.MethodsThe thirtyfive patients with IAH of postoperative abdominal trauma in intensive care unit (ICU)of the second affiliated hospital of Fujian medical college from September 2008 to March 2014 were retrospecively analysed,including early CBP group (seventeen cases) and control group (eighteen cases).The cases with abdominal compartment syndrome (ACS)，the duration of IAH,prognosis,the mean arterial pressure,the level of oxygenation index(PaO2 /FiO2),the average of IAP and the lactic acid level of two groups were compared.ResultsThe cases of ACS and death in early stage of CBP(four cases and two cases respectively ) were significantly decreased than those in control group (thirteenthree cases and nine cases respectively)(χ2=8.30,5.93;P＜0.05）；The duration of IAH ［（3.22±1.47）d］ in early stage of CBP was significantly shorter than that in control group［（6.53± 2.38）d］(t=4.91,P＜0.05).The mean arterial pressure［（92.17±8.37）mmHg］ （1mmHg=0.133kpa）,the level of PaO2/FiO2(309.8±74.7）in early stage of CBP were higher than those in control group ［（68.92±8.35)mmHg,（256.6±85.5）］(t=8.22,2.04;P＜0.05）.The average of IAP （11.81±1.59）and the lactic acid level ［（2.05±1.31）mmol/L］ in early CBP were lower than those in control group,［（18.38±3.87），（3.35±1.44）mmol/L］ ，(t=6.50，2.79;P＜0.05）.Conclusion The use of early CBP in IAH after abdominal trauma operation is the effective treatment measure for reducing IAP and prevention of ACS.
