Abstract:Thymidylate synthase(TS) is the major enzyme of antitumor drugs. Pemetrexed disodium and S-1 are the most common TS inhibitors, and widely used in the treatment of non-small cell lung cancer (NSCLC) because of their curative effect and mild side-effect. In this review, we will mainly discuss the research progress of thymidylate synthase and its inhibitors in NSCLC.
鲁葆华 张同梅 李宝兰. 胸苷酸合酶及其抑制剂与非小细胞肺癌的研究进展[J]. 中华诊断学电子杂志, 2016, 4(4): 255-.
Lu Baohua,Zhang Tongmei,Li Baolan. Research of thymidylate synthase and its inhibitors in non-small cell lung cancer. zhzdx, 2016, 4(4): 255-.