1Department of Internal Medicine,Yuanyang Branch of Shanghai Ruijin Hospital,Shanghai 200031,China;2Department of Endocrinology and Metabolism Medicine,Shanghai Ruijin Hospital,Shanghai 200025,China;3Department of Respiratory Medicine,Shanghai Six People’s Hospital,Shanghai 200031,China
Abstract：The airway inflammation and remodeling is the pathophysiological basis of many common chronic lung diseases.It is difficult that the single indicator fully reflects the level and prognosis airway inflammation and remodeling.Because it involves the interaction of a variety of inflammatory cells,cellular components and inflammatory mediators,which can result in the certain heterogeneity of pathophysiology and clinical manifestations.This review focuse don asthma,chronic obstructive pulmonary disease,pulmonary hypertension and discusses biomarkers that has been researched for their usefulness to phenotype chronic inflammatory lung diseases which cause remodeling of the lung′s architecture.The goal is to evaluate the airway inflammation and remodeling during the chronic lung disease and to provide more treatment options for reference.
郭凯1施建元1顾雪明1汤正义2殷少军3. 生物标志物在气道炎症及重塑诊治中的应用[J]. 中华诊断学电子杂志, 2017, 5(3): 216-218.
Guo Kai1,Shi Jianyuan1,Gu Xueming1,Tang Zhengyi2,Yin Shaojun3. The application of biological markers in the diagnosis and treatment of airway inflammation and remodeling. zhzdx, 2017, 5(3): 216-218.
