Research progress on the correlation of intestinal flora with antitubercular agents and antitubercular agentsinduced liver injury
Liu Yan1, Tang Shenjie2
1Department of Infectious Disease, Taicang Affiliated Hospital of Soochow University, the First People′s Hospital of Taicang, Taicang 215400, China; 2Clinical Medicine Center, Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing Chest Hospital, Affiliated to Capital Medical University, Beijing 101149, China
Abstract：The bacteria mycobacterium tuberculosis is the primary cause of tuberculosis, a deadly chronic infectious disease. Effective antituberculous therapy is essential for controlling the tuberculosis epidemic. Since the intestinal flora serves as the "second genome" of humans, maintaining its equilibrium is critical for maintaining good health. Antibiotics, which are commonly used to treat tuberculosis, may disturb the equilibrium of the intestinal flora. Intestinal flora imbalance has been linked to liver damage caused by antituberculosis drugs, and it can influence how well treatments work and how the disease develops. This paper discusses the impact of antituberculosis medications on intestinal flora, the imbalance of intestinal flora and liver damage caused by antituberculosis medications, and the repercussions of changes in intestinal flora on the host.
刘艳 唐神结. 肠道菌群与抗结核药及其所致肝损伤的相关性研究进展[J]. 中华诊断学电子杂志, 2023, 11(2): 82-86.
Liu Yan, Tang Shenjie. Research progress on the correlation of intestinal flora with antitubercular agents and antitubercular agentsinduced liver injury. zhzdx, 2023, 11(2): 82-86.
