Progress of proteomics in the diagnosis of Parkinson′s disease
Fan Kaiyang1, Sun Qiang1, Zhang Yu3, Lu Lili2, Song Jiaxin2, Wang Zhaojing2, Ma Li2
1Medical Service, the Affiliated Hospital of Jining Medical University, Jining 272029,China; 2Department of Epidemiology, Dalian Medical University, Dalian 116044, China; 3Dalian Center for Disease Control and Prevention, Dalian 116021, China
Abstract：Parkinson′s disease is the second most common neurodegenerative disease in humans. The pathogenesis of Parkinson′s disease is currently unclear. Using proteomics approach to study the disease can help us to have a deeper understanding of the disease, and it is of great significance to explore its pathogenesis, to find reliable related biomarkers, and to develop new treatments. The author introduces the application of proteomics in the study of Parkinson′s disease from two aspects. On the one hand, the proteins is studies by acquiring the brain tissue and cerebrospinal fluid of the patients. On the other hand, the desired tissue is obtained for protein tissue research by making animal models of Parkinson′s disease.
樊开阳 孙强 张瑜 卢丽丽 宋佳鑫 王兆京 马莉. 蛋白质组学在帕金森病诊断中的研究进展[J]. 中华诊断学电子杂志, 2019, 7(1): 63-65.
Fan Kaiyang1, Sun Qiang1, Zhang Yu3, Lu Lili2, Song Jiaxin2, Wang Zhaojing2, Ma Li2. Progress of proteomics in the diagnosis of Parkinson′s disease. zhzdx, 2019, 7(1): 63-65.
