The diagnostic value of the triglyceride-glucose index in predicting the risk of non-alcoholic fatty liver disease in physical examination population
Zhang Meiyu1, Wu Shengli2, Xiang Weiting2, Sun Kehong1, Li Nong2
1Health Management and Physical Examination Center, 2Endocrine Metabolic Center, Karamay Integrated Chinese and Western Hospital (Municipal People′s Hospital), Karamay 834000, China
Abstract：ObjectiveTo explore the predictive value of triglycerideglucose (TyG) index on the risk of nonalcoholic fatty liver disease (NAFLD) in physical examination population. MethodsFrom December 2018 to December 2019, a total of 8860 employees from Xinjiang Oilfield Company and Western Drilling Company who underwent physical examinations in the Karamay Integrated Chinese and Western Hospital (Municipal People′s Hospital) were chosen as the research subjects. The subjects′ general clinical data, blood biochemical indexes, and ultrasonic examination results were collected, and the TyG index was calculated. The risk factors for NAFLD were studied using multivariate logistic regression. The receiver operating characteristic (ROC) curve was used to assess the predictive value of the TyG index for NAFLD. ResultsNAFLD affected 3261 patients. The TyG index, age, systolic blood pressure, abdominal girth, and alanine aminotransferase were found to be independent risk factors for NAFLD, with ORs of 3.294(2.933-3.699), 1.013(1.006-1.020), 1.007(1.001-1.012), 1.092(1.085-1.100), and 1.029(1.026-1.033)(all P＜0.05). The area under the curve (AUC) of TyG index was 0.818 according to the ROC curve analysis, and the cut-off value of TyG index in diagnosing NAFLD was 4.310. ConclusionThe TyG index can better predict NAFLD risk and be used as an effective indicator for screening NAFLD high-risk populations.
张梅玉 吴胜利 向蔚婷 孙克红 李农. 体检人群甘油三酯葡萄糖指数对非酒精性脂肪性肝病发病风险的诊断价值[J]. 中华诊断学电子杂志, 2022, 10(3): 152-157.
Zhang Meiyu1, Wu Shengli2, Xiang Weiting2, Sun Kehong1, Li Nong2. The diagnostic value of the triglyceride-glucose index in predicting the risk of non-alcoholic fatty liver disease in physical examination population. zhzdx, 2022, 10(3): 152-157.
